Newcastle Laboratories

ACTH precursors, plasma

Clinical Background:

To differentiate between pituitary and ectopic causes of Cushing's syndrome.

ACTH precursor concentrations are elevated in patients with ectopic tumours compared with patients pituitary microadenomas.

To differentiate between pituitary and ectopic causes of Cushing's syndrome.

ACTH precursor concentrations are elevated in patients with ectopic tumours compared with patients pituitary microadenomas.

Test Documents

Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Lithium Heparin plasma

    Lithium Heparin plasma

  • Specimen Container Paediatric:

    Lithium Heparin plasma

     

    Lithium Heparin plasma

     

  • Minimum Volume Adult:

    2 x 0.5 mL 

    2 x 0.5 mL 

  • Minimum Volume Paediatric:

    2 x 0.5 mL 

    2 x 0.5 mL 

  • Special Requirement:

    Sample to be send to the laboratory immediately to be spun within 20 minutes of sampling.

    Pro forma to be completed by ward, including full clinical and patient details

    Sample to be send to the laboratory immediately to be spun within 20 minutes of sampling.

    Pro forma to be completed by ward, including full clinical and patient details

  • Sample Stability:

    Store at -20°C

    Store at -20°C

  • Transport Requirements:

    Must be transported on dry ice and sent early in the week

    Must be transported on dry ice and sent early in the week

  • Reference Ranges:

    Upper range of normal 100pmol/L (female)

    Upper range of normal 100pmol/L (female)

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

    - For external users: TNU-Tr.duty.biochemist@nhs.net

    - For Trust users: DutyBiochemist@nuth.nhs.uk

  • Specialist Test:

    Yes

    Yes

  • Specialist Contact Name:

    Endocrine Lab

    Endocrine Lab

  • Specialist Telephone:

    0191 282 4025

    0191 282 4025

Availability:

Sample sent to an external laboratory for testing

Turn Around:

Within 2 weeks

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