Newcastle Laboratories

vWF Multimers

Clinical Background:

The structure of von Willebrand factor in patients can be determined by electrophoresis of the plasma after treatment to break down the bonds in the molecule. This gives a 'ladder' effect with the ...

The structure of von Willebrand factor in patients can be determined by electrophoresis of the plasma after treatment to break down the bonds in the molecule. This gives a 'ladder' effect with the multimers being shown as bands from the highest weight to the lowest weight. Absence of particular bands is used to confirm the type of vWD and sub-type the Type 2 disorders

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Test Details

  • Discipline:

    Haemostasis

    Haemostasis

  • Specimen Container Adult:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Specimen Container Paediatric:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Minimum Volume Adult:

    5.4mL

    5.4mL

  • Minimum Volume Paediatric:

    2.6mL

    2.6mL

  • Special Requirement:

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

  • Sample Stability:

    4 hrs

    4 hrs

  • Transport Requirements:

    Samples should be transported to lab without delay

    Samples should be transported to lab without delay

  • Freq Analysis:

    Fortnightly

    Fortnightly

  • Add On Test:

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    tnu-tr.bloodsciencesadditions@nh...

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    No current scheme available

    No current scheme available

  • Reference Ranges:

    Interpretation provided by Haematology medical staff.

    Interpretation provided by Haematology medical staff.

  • Other Info:

    Analysis of vW multimer structure.

    Performed as part of a vW Screen when considered clinically relevant.

    Analysis of vW multimer structure.

    Performed as part of a vW Screen when considered clinically relevant.

  • Routine Email:

  • Specialist Test:

    Yes

    Yes

  • Specialist Contact Name:

    Haematology/Haemostasis Health Care Scientist

    Haematology/Haemostasis Health Care Scientist

  • Specialist Telephone:

    0191 213 9758

    0191 213 9758

Availability:

All testing performed at RVI Haematology laboratory and available during routine hours, Monday to Friday. Testing is usually performed on a monthly basis, depending on batch size availability.

Turn Around:

Usually within 14 days.

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