Theophylline, serum
Clinical Background:
Theophylline and the related methylxanthines share several pharmacological actions with potential therapeutic applications. They relax smooth muscle so relieving or preventing bronchoconstriction. ...
Theophylline and the related methylxanthines share several pharmacological actions with potential therapeutic applications. They relax smooth muscle so relieving or preventing bronchoconstriction. They also stimulate the CNS, cardiac muscle and act on the kidney to produce a diuresis.Theophylline is used to treat asthma and stable chronic obstructive pulmonary disease predominantly in small children and the elderly who have difficulty in using inhalers and in patients with predominantly nocturnal symptoms.
Test Details
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Discipline:
Biochemistry
Biochemistry
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Specimen Container Adult:
Serum (SST or plain tube)
Serum (SST or plain tube)
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Specimen Container Paediatric:
Serum (SST or plain tube)
Serum (SST or plain tube)
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Minimum Volume Adult:
1 mL blood
1 mL blood
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Minimum Volume Paediatric:
0.5 mL blood
0.5 mL blood
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Special Requirement:
Trough sample recommended
Trough sample recommended
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Sample Stability:
Unseparated sample: unknown
Separated sample: unknown at 15-25°C, 7 days at 2-8°C, 60 days at -20°CUnseparated sample: unknown
Separated sample: unknown at 15-25°C, 7 days at 2-8°C, 60 days at -20°C -
Reference Ranges:
Adult Therapeutic Range: 10 - 20 mg/L
Adult Therapeutic Range: 10 - 20 mg/L
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Other Info:
Lithium heparin sample also acceptable
Lithium heparin sample also acceptable
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Routine Contact Name:
Duty biochemist
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Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719
Freeman: 0191 244 8889
RVI: 0191 282 9719
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Routine Email: