Newcastle Laboratories

Sodium, urine

Clinical Background:

Sodium is the major extracellular cation in the body and along with its associated anions, contributes to most of the plasma osmolality and therefore plays an important role in water and electrolyt...

Sodium is the major extracellular cation in the body and along with its associated anions, contributes to most of the plasma osmolality and therefore plays an important role in water and electrolyte homeostasis. The amount of sodium in the body is a reflection of the balance between sodium intake and output. The body requires only 1 to 2 mmol/day, and the excess is excreted by the kidneys. Measurement of sodium in urine provides an indication of sodium balance, and whether sodium loss is of renal or extra-renal origin, e.g. gastrointestinal loss.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Urine, random or 24h (no preservative)

    Urine, random or 24h (no preservative)

  • Specimen Container Paediatric:

    Urine, random or 24h (no preservative)

    Urine, random or 24h (no preservative)

  • Minimum Volume Adult:

    1 mL aliquot

    1 mL aliquot

  • Minimum Volume Paediatric:

    1 mL aliquot

    1 mL aliquot

  • Sample Stability:

    Urine samples are stable at room temperature and 4°C for 7 days.

    For long-term storage, samples can be stored at -20°C.

    Urine samples are stable at room temperature and 4°C for 7 days.

    For long-term storage, samples can be stored at -20°C.

  • Quality Assurance:

    WEQAS

    WEQAS

  • Interpretation:

    Urine sodium excretion varies with dietary intake.

    In hypervolaemic states, urine sodium <10 mmol/L indicates extra-renal loss of sodium, e.g. vomiting/diarrhea; urine sodium >20 mmol/L indicates...

    Urine sodium excretion varies with dietary intake.

    In hypervolaemic states, urine sodium <10 mmol/L indicates extra-renal loss of sodium, e.g. vomiting/diarrhea; urine sodium >20 mmol/L indicates renal sodium loss, e.g. diuretics, osmotic diuresis, mineralocorticoid insufficiency.

    In hypervolaemic states, urine sodium <10 mmol/L indicates nephrotic syndrome, liver cirrhosis and congestive heart failure; urine sodium >20 mmol/L indicates renal failure.

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  • Reference Ranges:

    24 hour urine collection:

    Male:          6 - <10 years:    41 - 115 mmol/24h

                       10 - 14 years:    63 - 177 mmol/24h

    Female:      6 - <10 years:    20 - 69 mmol/24h

                     ...

    24 hour urine collection:

    Male:          6 - <10 years:    41 - 115 mmol/24h

                       10 - 14 years:    63 - 177 mmol/24h

    Female:      6 - <10 years:    20 - 69 mmol/24h

                       10 - 14 years:    48 - 168 mmol/24h

    Male and female, >14 years: 40 - 220 mmol/24h

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  • Other Info:

    Acid rinsed bottle acceptable

    Acid rinsed bottle acceptable

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

All times
All sites

Turn Around:


Non-urgent: within 1 day

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