SNP array for haematological malignancy
Clinical Background:
Single Nucleotide Polymorphism array testing can identify genome wide copy number changes (gains/losses/gene amplifications) and loss of heterozygosity (LOH). These genomic changes can help in the ...
Single Nucleotide Polymorphism array testing can identify genome wide copy number changes (gains/losses/gene amplifications) and loss of heterozygosity (LOH). These genomic changes can help in the diagnosis and prognosis of haematological malignancies. SNP array is a primary test in ALL and CLL and will be performed in AML, MDS and MPN cases where karyotyping has been unsuccessful. SNP array can be performed on liquid samples as well as FFPE.
Test Details
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Discipline:
NEHODS
NEHODS
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Specimen Container Adult:
Lithium heparin or EDTA for liquid samples and FFPE for tissue biopsies
Lithium heparin or EDTA for liquid samples and FFPE for tissue biopsies
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Specimen Container Paediatric:
Lithium heparin or EDTA for liquid samples. Fresh samples also accepted.
Lithium heparin or EDTA for liquid samples. Fresh samples also accepted.
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Minimum Volume Adult:
3ml
3ml
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Minimum Volume Paediatric:
3ml
3ml
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Special Requirement:
Please complete NEHODS request form
Please complete NEHODS request form
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Sample Stability:
Not suitable for FFPE material
Not suitable for FFPE material
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Transport Requirements:
Samples should be sent to laboratory immediately.
Samples should be sent to laboratory immediately.
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Freq Analysis:
Daily
Daily
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Add On Test:
Can be added to any genetics sample where DNA has been stored
Can be added to any genetics sample where DNA has been stored
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Quality Assurance:
UK NEQAS
UK NEQAS
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Interpretation:
By genetics clinical scientist
By genetics clinical scientist
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Reference Ranges:
N/A
N/A
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Factors Affecting Result:
Quality and size of sample
Quality and size of sample
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Referenced Documents:
N/A
N/A