SmRNP Antibodies
Clinical Background:
SmRNP antibodies may help in the differentiation of connective tissue diseases. In SLE SmRNP antibodies may occur in conjunction with antibodies to ds-DNA and Sm. When SmRNP antibodies occur alone ...
SmRNP antibodies may help in the differentiation of connective tissue diseases. In SLE SmRNP antibodies may occur in conjunction with antibodies to ds-DNA and Sm. When SmRNP antibodies occur alone they point to a diagnosis of undifferentiated connective tissue disease (UCTD).
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum-SST
Serum-SST
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Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
0.5 ml
0.5 ml
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Special Requirement:
None
None
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Freq Analysis:
Daily
Daily
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Add On Test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to nuth.autoimmunity@nhs.net
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to nuth.autoimmunity@nhs.net
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Quality Assurance:
UK NEQAS for Antibodies to Nuclear and Related Antigens
UK NEQAS for Antibodies to Nuclear and Related Antigens
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Interpretation:
There is no relationship between the titre of anti-RNP antibody and disease activity.
There is no relationship between the titre of anti-RNP antibody and disease activity.
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Reference Ranges:
Normal Range: Negative
Normal Range: Negative
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Other Info:
SmRNP antibodies are detected as part of the ANA and Related antibodies assay and are reported as Negative or Positive.
SmRNP antibodies are detected as part of the ANA and Related antibodies assay and are reported as Negative or Positive.
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email: