Newcastle Laboratories

Serum Tryptase

Clinical Background:

Serum tryptase is raised acutely in anaphylaxis. It is particularly useful in anaesthetic allergy where it may help in the differential diagnosis of the acute reaction. However, normal levels do no...

Serum tryptase is raised acutely in anaphylaxis. It is particularly useful in anaesthetic allergy where it may help in the differential diagnosis of the acute reaction. However, normal levels do not exclude allergy as a cause of a reaction.

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Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Serum-SST

    Serum-SST

  • Specimen Container Paediatric:

    Serum-Plain tube

    Serum-Plain tube

  • Minimum Volume Adult:

    1 ml

    1 ml

  • Minimum Volume Paediatric:

    1 ml

    1 ml

  • Freq Analysis:

    Twice Weekly

    Twice Weekly

  • Add On Test:

    All urgent add ons via telephone on 0191 282 1890 and must be confirmed via email to 

    nuth.autoimmunity@nhs.net

    All urgent add ons via telephone on 0191 282 1890 and must be confirmed via email to 

    nuth.autoimmunity@nhs.net

  • Quality Assurance:

    UK NEQAS for Tryptase

    UK NEQAS for Tryptase

  • Interpretation:

    The three samples taken give information about levels of Tryptase immediately post reaction, during recovery and once a resting level has returned. It is therefore very important that all samples a...

    The three samples taken give information about levels of Tryptase immediately post reaction, during recovery and once a resting level has returned. It is therefore very important that all samples are taken, labelled accurately and sent to the laboratory quickly.

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  • Reference Ranges:

    Normal Range: 2 - 14 ug/L

    Normal Range: 2 - 14 ug/L

  • Other Info:

    Serum should be taken as soon as possible after the reaction (within 1 hour), a short time after the reaction (between 1 and 4 hours), as well as 24 hours later and labelled with the time of reacti...

    Serum should be taken as soon as possible after the reaction (within 1 hour), a short time after the reaction (between 1 and 4 hours), as well as 24 hours later and labelled with the time of reaction and time of sample post reaction. The two samples taken give information about levels of Tryptase immediately post reaction and also once a resting level has returned. It is therefore very important that BOTH samples are taken, labelled accurately and sent to the laboratory quickly.

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  • Routine Contact Name:

    Autoimmunity Lab

  • Routine Telephone:

    0191 282 1890

    0191 282 1890

  • Routine Email:

Availability:

Tryptase samples are tested twice a week, usually on Tuesday and Thursday.

Turn Around:

5 routine working days

Send To:

Department of Blood Sciences

Level 3
Leazes Wing
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP

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