Rheumatoid Factor
Clinical Background:
Rheumatoid Factors occur in a wide variety of conditions including viral infections, chronic bacterial infections, myeloma, lymphoma and connective tissue disease. Healthy elderly people may also h...
Rheumatoid Factors occur in a wide variety of conditions including viral infections, chronic bacterial infections, myeloma, lymphoma and connective tissue disease. Healthy elderly people may also have a positive Rheumatoid Factor. In Rheumatoid Arthritis the Rheumatoid Factor may be positive or negative, high titres are seen in progressive and extra-articular disease.
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum-SST
Serum-SST
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Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
1 ml
1 ml
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Sample Stability:
Unseparated sample: Unknown
Separated sample: 7 days at 4°CUnseparated sample: Unknown
Separated sample: 7 days at 4°C -
Freq Analysis:
Daily
Daily
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Add On Test:
All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address
tnu-tr.bloodsciencesadditions@nhs.net (internal)
or
Read MoreAll urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address
tnu-tr.bloodsciencesadditions@nhs.net (internal)
or
tnu-tr.bloodsciencesadditions@nhs.net (external)
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Quality Assurance:
UK NEQAS for General Autoimmune Serology
UK NEQAS for General Autoimmune Serology
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Interpretation:
In Rheumatoid Arthritis the Rheumatoid Factor may be positive or negative, high titres are seen in progressive and extra-articular disease.
In Rheumatoid Arthritis the Rheumatoid Factor may be positive or negative, high titres are seen in progressive and extra-articular disease.
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Reference Ranges:
Normal Range: 0 - 19 IU/ml
Normal Range: 0 - 19 IU/ml
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Other Info:
Plasma- Lithium Heparin also acceptable. Serial monitoring of Rheumatoid Factor is not recommended, as there is not a useful correlation with disease activity.
Plasma- Lithium Heparin also acceptable. Serial monitoring of Rheumatoid Factor is not recommended, as there is not a useful correlation with disease activity.
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email: