Rheumatoid Factor
Clinical Background:
Rheumatoid Factors occur in a wide variety of conditions including viral infections, chronic bacterial infections, myeloma, lymphoma and connective tissue disease. Healthy elderly people may also h...
Rheumatoid Factors occur in a wide variety of conditions including viral infections, chronic bacterial infections, myeloma, lymphoma and connective tissue disease. Healthy elderly people may also have a positive Rheumatoid Factor. In Rheumatoid Arthritis the Rheumatoid Factor may be positive or negative, high titres are seen in progressive and extra-articular disease.
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum (SST or plain tube)
Serum (SST or plain tube)
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Specimen Container Paediatric:
Serum (SST or plain tube)
Serum (SST or plain tube)
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
1 ml
1 ml
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Sample Stability:
Unseparated sample: Unknown
Separated sample: 24 hours at 15-25°C, 8 days at 2-8°C, 3 months at -20°C.Unseparated sample: Unknown
Separated sample: 24 hours at 15-25°C, 8 days at 2-8°C, 3 months at -20°C. -
Freq Analysis:
Daily
Daily
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Add On Test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address
nuth.autoimmunity@nhs.net
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address
nuth.autoimmunity@nhs.net
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Quality Assurance:
UK NEQAS for General Autoimmune Serology
UK NEQAS for General Autoimmune Serology
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Interpretation:
In Rheumatoid Arthritis the Rheumatoid Factor may be positive or negative, high titres are seen in progressive and extra-articular disease.
In Rheumatoid Arthritis the Rheumatoid Factor may be positive or negative, high titres are seen in progressive and extra-articular disease.
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Reference Ranges:
Normal Range: 0 - 19 IU/ml
Normal Range: 0 - 19 IU/ml
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Other Info:
Plasma- Lithium Heparin also acceptable. Serial monitoring of Rheumatoid Factor is not recommended, as there is not a useful correlation with disease activity.
Plasma- Lithium Heparin also acceptable. Serial monitoring of Rheumatoid Factor is not recommended, as there is not a useful correlation with disease activity.
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email:
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Specialist Email:
nuth.autoimmunity@nhs.net
nuth.autoimmunity@nhs.net