Proteinase-3 Antibodies
Clinical Background:
Proteinase 3 (PR3) antibodies are part of the first-line testing protocol for small vessel vasculitis alongside Myeloperoxidase (MPO) antibodies. Positive PR3 antibodies point towards granulomatous...
Proteinase 3 (PR3) antibodies are part of the first-line testing protocol for small vessel vasculitis alongside Myeloperoxidase (MPO) antibodies. Positive PR3 antibodies point towards granulomatous polyangiitis (GPA).
Test Details
-
Discipline:
Immunology
Immunology
-
Specimen Container Adult:
Serum-SST
Serum-SST
-
Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
-
Minimum Volume Adult:
1 ml
1 ml
-
Minimum Volume Paediatric:
1 ml
1 ml
-
Special Requirement:
None
None
-
Freq Analysis:
Daily
Daily
-
Add On Test:
All urgent add ons via telephone on : 0191 2821890, and must be confirmed via email to nuth.autoimmunity@nhs.net
All urgent add ons via telephone on : 0191 2821890, and must be confirmed via email to nuth.autoimmunity@nhs.net
-
Quality Assurance:
UK NEQAS for Autoimmune Serology ANCA and GBM
UK NEQAS for Autoimmune Serology ANCA and GBM
-
Interpretation:
None
None
-
Reference Ranges:
Normal Range: 0 - 0.9 Antibody Index (AI)
Normal Range: 0 - 0.9 Antibody Index (AI)
-
Other Info:
Reported as a number between 0.2 and 8.0 AI
Reported as a number between 0.2 and 8.0 AI
-
Routine Contact Name:
Autoimmunity Lab
-
Routine Telephone:
0191 2821890
0191 2821890
-
Routine Email: