Test Details

• Discipline:

  Biochemistry

  Biochemistry

• Specimen Container Adult:

  Plain universal container (random urine sample) or plain bottle (24 hour urine collection)

  Plain universal container (random urine sample) or plain bottle (24 hour urine collection)

• Specimen Container Paediatric:

  Plain universal container (random urine sample)

  Plain universal container (random urine sample)

• Minimum Volume Adult:

  1 mL aliquot

  1 mL aliquot

• Minimum Volume Paediatric:

  1 mL aliquot

  1 mL aliquot

• Sample Stability:

  at +15° to +25°C: 1 day
  at +2° to +8°C: 7 days
  at -20°C: 1 month

  at +15° to +25°C: 1 day
  at +2° to +8°C: 7 days
  at -20°C: 1 month

• Interpretation:

  Only very small quantities of protein are found in normal urine.
  Proteinuria may be due to renal damage or disease which can either be glomerular or tubular in origin.
  Glomerular proteinuria is the...

  Only very small quantities of protein are found in normal urine.
  Proteinuria may be due to renal damage or disease which can either be glomerular or tubular in origin.
  Glomerular proteinuria is the more common form; massive proteinuria is always of glomerular origin.
  Proteinuria may occur with normal renal function if abnormally large amounts of low molecular weight proteins are being produced, e.g. in Bence-Jones proteinuria, myoglobinuria and haemoglobinuria.
  In pregnant women elevated urine protein is associated with pre-eclampsia.
  Urine protein/creatinine ratio is commonly used to monitor high levels of proteinuria in patients with chronic kidney disease.
  In some individuals proteinuria may be persistent or transient-Transient proteinuria is usually mild and may occur only when individuals are in the upright position(orthostatic /postural), during illness or after vigorous exercise.

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• Reference Ranges:

  - 24h urine collection (g/24h)
  Adult:  <0.140

  - Random urine sample (mg/mmol creatinine)
  Children and adults: <15

  - 24h urine collection (g/24h)
  Adult:  <0.140

  - Random urine sample (mg/mmol creatinine)
  Children and adults: <15

• Factors Affecting Result:

  Hydration state

  Hydration state

• Routine Contact Name:

  Duty Biochemist

• Routine Telephone:

  Freeman: 0191 244 8889
  RVI: 0191 282 9719

  Freeman: 0191 244 8889
  RVI: 0191 282 9719

• Routine Email:

  nuth.dutybiochemist@nhs.net