Newcastle Laboratories

Pregnancy test, urine

Clinical Background:

In pregnancy human chorionic gonadotrophin (hCG) is produced by the placenta shortly after fertilisation. In normal pregnancy urine hCG levels rise rapidly to 50-250 IU/L by the day of the expected...

In pregnancy human chorionic gonadotrophin (hCG) is produced by the placenta shortly after fertilisation. In normal pregnancy urine hCG levels rise rapidly to 50-250 IU/L by the day of the expected menstrual period and peaks to 100,000 to 200,000 during the first trimester. In a normal pregnancy hCG may be detected in urine 7-10 days following conception.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Plain universal container (random urine sample)

    Plain universal container (random urine sample)

  • Specimen Container Paediatric:

    Plain universal container (random urine sample)

    Plain universal container (random urine sample)

  • Minimum Volume Adult:

    1 mL aliquot

    1 mL aliquot

  • Minimum Volume Paediatric:

    1 mL aliquot

    1 mL aliquot

  • Special Requirement:

    First morning urine is the preferred specimen

    First morning urine is the preferred specimen

  • Sample Stability:

    at +2° to +8°C 48 hours
    at -20°C 3 months

    at +2° to +8°C 48 hours
    at -20°C 3 months

  • Interpretation:

    hCG can be detected in urine at concentrations of 25 mIU/mL or greater

    hCG can be detected in urine at concentrations of 25 mIU/mL or greater

  • Reference Ranges:

    Detection limit 25 IU/L (HCG)
    Weak positives should be resampled and retested after 48h

    Detection limit 25 IU/L (HCG)
    Weak positives should be resampled and retested after 48h

  • Factors Affecting Result:

    Drugs containing hCG may interfere and produce misleading results.
    False positive pregnancy tests have been observed in patients with enterocystoplasties. Confirmation of the result must be made wit...

    Drugs containing hCG may interfere and produce misleading results.
    False positive pregnancy tests have been observed in patients with enterocystoplasties. Confirmation of the result must be made with a serum hCG analysis.
    Inconsistent results may be found in urine samples containing excessive amounts of bacteria.

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  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

Assayed daily, analysed at RVI and Freeman

Turn Around:

Within 1 day

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