Porphobilinogen screen, urine
Clinical Background:
Used in the investigation of acute unexplained abdominal pain or neurological symptoms where a undetectable concentration of porphobilinogen would exclude an acute porphyria as the cause.
Used in the investigation of acute unexplained abdominal pain or neurological symptoms where a undetectable concentration of porphobilinogen would exclude an acute porphyria as the cause.
Test Documents
Test Details
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Discipline:
Biochemistry
Biochemistry
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Specimen Container Adult:
Plain universal container
Plain universal container
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Specimen Container Paediatric:
Plain universal container
Plain universal container
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Minimum Volume Adult:
2 mL
2 mL
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Minimum Volume Paediatric:
2 mL
2 mL
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Special Requirement:
Sample must be protected from light.
Sample must be protected from light.
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Sample Stability:
Unknown at 15-25°C, 2 days at 2-8°C, 1 months at -20°C
Unknown at 15-25°C, 2 days at 2-8°C, 1 months at -20°C
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Interpretation:
Light results in degradation of the porphyrins which will produce a falsely low result.
Interfering compounds e.g. urobiliogen removed during procedure.Light results in degradation of the porphyrins which will produce a falsely low result.
Interfering compounds e.g. urobiliogen removed during procedure. -
Reference Ranges:
PBG:creatinine ratio less than 1.5 umol/mmol.
PBG:creatinine ratio less than 1.5 umol/mmol.
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Factors Affecting Result:
Light causes degradation of porphyrins
Light causes degradation of porphyrins
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Routine Contact Name:
Duty biochemist
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Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719Freeman: 0191 244 8889
RVI: 0191 282 9719 -
Routine Email: