Newcastle Laboratories

Phosphate, serum

Clinical Background:

Phosphate levels may be used in the diagnosis and management of a variety of disorders including bone, parathyroid and renal disease. 88% of the phosphorus contained in the body is localized in bon...

Phosphate levels may be used in the diagnosis and management of a variety of disorders including bone, parathyroid and renal disease. 88% of the phosphorus contained in the body is localized in bone in the form of hydroxyapatite. The remainder is involved in intermediary metabolism. Phosphorus occurs in blood in the form of inorganic phosphate and organically bound phosphoric acid. Serum phosphate concentrations are dependent on meals and variation in the secretion of hormones such as parathyroid hormone (PTH) and may vary widely. Hypophosphataemia may have three general causes: shift of phosphate between extracellular to intracellular compartments, renal phosphate wasting, and loss from the gastrointestinal tract. Hyperphosphataemia is usually secondary to an inability of the kidneys to excrete phosphate. Other factors may relate to increased intake or a shift of phosphate from the tissues into the extracellular fluid.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Serum (SST or plain tube)

    Serum (SST or plain tube)

  • Specimen Container Paediatric:

    Serum (SST or plain tube)

    Serum (SST or plain tube)

  • Minimum Volume Adult:

    1 mL blood

    1 mL blood

  • Minimum Volume Paediatric:

    0.5 mL blood

    0.5 mL blood

  • Sample Stability:

    Unseparated: one day

    Separated: 24 hours at 15-25C, 4 days at 2-8C, 1 year at -20C

    Unseparated: one day

    Separated: 24 hours at 15-25C, 4 days at 2-8C, 1 year at -20C

  • Reference Ranges:

    < 4w: 1.30 - 2.60 mmol/L
    4w - 1y: 1.30 - 2.40 mmol/L
    1y - 16y: 0.90 - 1.80 mmol/L
    16y and over: 0.80 - 1.50 mmol/L

    < 4w: 1.30 - 2.60 mmol/L
    4w - 1y: 1.30 - 2.40 mmol/L
    1y - 16y: 0.90 - 1.80 mmol/L
    16y and over: 0.80 - 1.50 mmol/L

  • Other Info:

    lithium heparin plasma sample also acceptable

    lithium heparin plasma sample also acceptable

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

Analysed on both sites

Available 24/7

Turn Around:

Urgent: Within 1 hour

Non-urgent: Within 4 hours

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