Parvovirus B19 IgM
Clinical Background:
This is a serological assay used to detect IgM antibodies to Parvovirus B19. It is used as the diagnostic test for recent parvovirus B19 infection. IgM antibodies are produced early in infection an...
This is a serological assay used to detect IgM antibodies to Parvovirus B19. It is used as the diagnostic test for recent parvovirus B19 infection. IgM antibodies are produced early in infection and normally persist for about 4 weeks. Parvovirus is responsible for 'slapped cheek disease' (erythema infectiosum) in children and also rash and arthralgia in adults. It can cause anaemia and aplasia in those with underlying haemoglobinopathies and immunosuppression. Low level IgM results can be non-specific and some samples are sent for Parvovirus PCR to confirm the diagnosis. IgM response may be absent or delayed in the immunocompromised and a parvovirus PCR should also be sent for diagnosis. I
Read MoreTest Details
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Discipline:
Microbiology
Microbiology
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Specimen Container Adult:
Clotted blood - Gold SST
Clotted blood - Gold SST
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Specimen Container Paediatric:
Clotted blood
Clotted blood
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Minimum Volume Adult:
5 ml
5 ml
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Minimum Volume Paediatric:
1 ml
1 ml
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Special Requirement:
Send to laboratory as quickly as possible. If delays likely, refrigerate at 2-8 deg C
Send to laboratory as quickly as possible. If delays likely, refrigerate at 2-8 deg C
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Sample Stability:
Stable for up to 24 hours
Stable for up to 24 hours
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Transport Requirements:
Standard
Standard
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Add On Test:
Possible up to 5 days
Possible up to 5 days
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Quality Assurance:
UK National External Quality Assurance Scheme (UKNEQAS)
UK National External Quality Assurance Scheme (UKNEQAS)
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Reference Ranges:
None availableNone available -
Factors Affecting Result:
If delays likely, refrigerate at 2-8 deg C
If delays likely, refrigerate at 2-8 deg C