Oxalate, urine
Clinical Background:
A raised urinary oxalate can result in the formation of renal stones which are predominantly composed of the sparingly soluble salt of calcium oxalate. Causes of hyperoxaluria include ingestion of ...
A raised urinary oxalate can result in the formation of renal stones which are predominantly composed of the sparingly soluble salt of calcium oxalate. Causes of hyperoxaluria include ingestion of oxalate rich foods, increased GI absorption of oxalate when there is severe fat malabsorption and rarely inherited disorders of metabolism such as primary oxaluria. An oxalate is commonly measured in urine in the investigation of renal calculi.
Test Details
-
Discipline:
Biochemistry
Biochemistry
-
Specimen Container Adult:
Plain universal container for random urine sample, or acid-rinsed bottle for 24 hour urine collection
Plain universal container for random urine sample, or acid-rinsed bottle for 24 hour urine collection
-
Specimen Container Paediatric:
Plain universal container (randome urine sample)
Plain universal container (randome urine sample)
-
Minimum Volume Adult:
2 mL
2 mL
-
Minimum Volume Paediatric:
1 mL
1 mL
-
Special Requirement:
For external users: samples must be acidified to pH<2.
Patient should refrain from excess vitamin C for at least 48h prior to collection.
For external users: samples must be acidified to pH<2.
Patient should refrain from excess vitamin C for at least 48h prior to collection.
-
Interpretation:
An increased excretion of oxalate can be attributed to increases in:
• Ingestion of oxalate rich foods, e.g. rhubarb.
• Formation of oxalate due to metabolic defects such as in primary hyperoxaluri...Read MoreAn increased excretion of oxalate can be attributed to increases in:
• Ingestion of oxalate rich foods, e.g. rhubarb.
• Formation of oxalate due to metabolic defects such as in primary hyperoxaluria
• Absorption of oxalate in a number of gastrointestinal disorders that produce severe fat malabsorption including patients with inflammatory bowel disease, ileal resection, and pancreatic insufficiency. -
Reference Ranges:
24h urine (mmol/24h)
Adult male: 0.08 – 0.49 mmol/24 hrs
Adult female: 0.04 – 0.32 mmol/24 hrs
Children: 0.14-0.42 mmol/24 hrs
Random urine (mmol/mmol creatinine)<1 yr: 0.015 – 0.260
1-4 yrs: 0.011...
Read More24h urine (mmol/24h)
Adult male: 0.08 – 0.49 mmol/24 hrs
Adult female: 0.04 – 0.32 mmol/24 hrs
Children: 0.14-0.42 mmol/24 hrs
Random urine (mmol/mmol creatinine)<1 yr: 0.015 – 0.260
1-4 yrs: 0.011-0.120
5-11 yrs: 0.006-0.150
>12 yrs: 0.002-0.083
<1 yr: 0.015 – 0.260
1-4 yrs: 0.011-0.120
5-11 yrs: 0.006-0.150
>12 yrs: 0.002-0.083
-
Routine Contact Name:
Duty biochemist
-
Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719Freeman: 0191 244 8889
RVI: 0191 282 9719 -
Routine Email: