Newcastle Laboratories

Osmolality, serum

Clinical Background:

Serum osmolality is a useful initial test when investigating the cause of hyponatraemia and in identifying a raised osmolal gap for suspected poisoning.
Calculated osmolarity = 2 (Na+) + glucose + u...

Serum osmolality is a useful initial test when investigating the cause of hyponatraemia and in identifying a raised osmolal gap for suspected poisoning.
Calculated osmolarity = 2 (Na+) + glucose + urea
The difference between the measured osmolality and the calculated is known as the osmolal gap and is normally less than 10 mOsm/kg.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Serum (SST or plain tube)

    Serum (SST or plain tube)

  • Specimen Container Paediatric:

    Serum (SST or plain tube)

    Serum (SST or plain tube)

  • Minimum Volume Adult:

    1 mL blood

    1 mL blood

  • Minimum Volume Paediatric:

    0.5 mL blood

    0.5 mL blood

  • Sample Stability:

    Unseparated sample: Unknown

    Separated samples:

    12 hrs at 20-25C

    3 days at 4-8C

    3 months at -20C

    Unseparated sample: Unknown

    Separated samples:

    12 hrs at 20-25C

    3 days at 4-8C

    3 months at -20C

  • Reference Ranges:

    275-295 mmol/Kg 

    275-295 mmol/Kg 

  • Routine Contact Name:

    Duty biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

24/7, analysed at RVI and Freeman

Turn Around:

Within 1 day

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