Non-Blood body Fluids
Clinical Background:
Cell counts, WBC differential and morphology reports from cytospin preparations are performed on body fluids to assess for infection or haematological malignancy.
Fluid types include CSF, Ascetic F...
Cell counts, WBC differential and morphology reports from cytospin preparations are performed on body fluids to assess for infection or haematological malignancy.
Fluid types include CSF, Ascetic Fluid, PD fluid, Synovial fluid, bronchoalveolar lavage (BAL) fluid and pleural fluid.
CSF counts and cytospin for suspected haematological malignancy
CSF screening for trypanosomiasis
Cell counts including WBC and differential counts of neutrophils, mononuclear cells and eosinophils on Ascetic fluid, Pleural fluid, Synovial fluid/Knee aspirates, PD fluids for suspected infection.
Note: Body fluids for suspected malignancy and joint fluid crystals should be sent to cytology
CSF counts for suspected meningitis should be sent to microbiology
Please refer to Trust protocol for CSF counts in suspected SAH
Test Details
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Discipline:
Haematology
Haematology
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Specimen Container Adult:
Sample should be taken into EDTA (purple top) adult tube for all samples with the exception of CSF. CSF samples should be taken into a universal container.
Sample should be taken into EDTA (purple top) adult tube for all samples with the exception of CSF. CSF samples should be taken into a universal container.
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Specimen Container Paediatric:
Sample should be taken into EDTA (purple top) adult tube for all samples with the exception of CSF. CSF samples should be taken into a Universal container.
Sample should be taken into EDTA (purple top) adult tube for all samples with the exception of CSF. CSF samples should be taken into a Universal container.
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Sample Stability:
4 hours Room Temperature. 24 hours 4oC.
CSF samples for Trypanosomiasis 1 hour.
4 hours Room Temperature. 24 hours 4oC.
CSF samples for Trypanosomiasis 1 hour.
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Transport Requirements:
ASAP. Urgent for CSF counts.
ASAP. Urgent for CSF counts.
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Add On Test:
tnu-tr.bloodsciencesadditions@nhs.net (external)
tnu-tr.bloodsciencesadditions@nhs.net (external)
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Interpretation:
Interpretation should take into account the numerical results of the cell count, WBC differential and specific morphology as well as the clinical context. Contact Haematology for further advice or ...
Read MoreInterpretation should take into account the numerical results of the cell count, WBC differential and specific morphology as well as the clinical context. Contact Haematology for further advice or referral.
Additional tests including flow cytometry and cytogenetics may be added onto the specimen when appropriate.
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Reference Ranges:
Variable depending on sample type. See specific departmental guidelines or contact haematology for further advice.
Variable depending on sample type. See specific departmental guidelines or contact haematology for further advice.
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Factors Affecting Result:
Adequate volume
Adequate mixing
Clots in sample
Sample haemolysis
Storage Temperature
Age of specimen
Adequate volume
Adequate mixing
Clots in sample
Sample haemolysis
Storage Temperature
Age of specimen
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Routine Contact Name:
RVI or Freeman Section Leaders
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Routine Telephone:
RVI: 0191 2820332, Freeman: 0191 2231195
RVI: 0191 2820332, Freeman: 0191 2231195
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Specialist Test:
Haematology and Haemostasis Healthcare Scientist
Haematology and Haemostasis Healthcare Scientist
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Specialist Contact Name:
Haematology/Haemostasis Health Care Scientist
Haematology/Haemostasis Health Care Scientist
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Specialist Telephone:
0191 2139758
0191 2139758
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Specialist Email:
alison.brown93@nhs.net
alison.brown93@nhs.net