Test Details

• Discipline:

  Biochemistry

  Biochemistry

• Specimen Container Adult:

  EDTA plasma

  EDTA plasma

• Specimen Container Paediatric:

  EDTA plasma

   

  EDTA plasma

   

• Minimum Volume Adult:

  2 mL blood

  2 mL blood

• Minimum Volume Paediatric:

  1 mL blood

  1 mL blood

• Special Requirement:

  To investigate cause of hypoglycaemia, collect sample during a hypoglycaemic episode or following a monitored prolonged fast.

  Lithium heparin sample is NOT acceptable.

  To investigate cause of hypoglycaemia, collect sample during a hypoglycaemic episode or following a monitored prolonged fast.

  Lithium heparin sample is NOT acceptable.

• Sample Stability:

  Unseparated whole blood 4 hours at 4°C

  Separated plasma or serum 2 months at -20°C

  Unseparated whole blood 4 hours at 4°C

  Separated plasma or serum 2 months at -20°C

• Transport Requirements:

  Local (NuTH) requests:  Send samples to the laboratory at ambient temperature.  Samples should be forwarded to the RVI for processing.  N.B. Check if other tests (e.g. blood spot acylcarnitines) ar...

  Local (NuTH) requests:  Send samples to the laboratory at ambient temperature.  Samples should be forwarded to the RVI for processing.  N.B. Check if other tests (e.g. blood spot acylcarnitines) are required before processing the sample.

  External requests: send frozen plasma or serum to RVI.

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• Reference Ranges:

  When analysed as part of an intermediary metabolite profile, results are reported with an interpretative comment.

  Reference ranges are otherwise as follows:

  Non-fasting: < 0.9 mmol/L

  Fasting (overa...

  When analysed as part of an intermediary metabolite profile, results are reported with an interpretative comment.

  Reference ranges are otherwise as follows:

  Non-fasting: < 0.9 mmol/L

  Fasting (overall range): 0.5 - 2.8 mmol/L

  15h fast: 0.5 - 1.6 mmol/L

  20h fast: 0.6 - 2.6 mmol/L

  24h fast: 1.0 - 2.8 mmol/L

   

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• Factors Affecting Result:

  Heparin (stimulates lipoprotein lipase therefore NEFA release from triglycerides).
  Haemolysis

  Heparin (stimulates lipoprotein lipase therefore NEFA release from triglycerides).
  Haemolysis

• Routine Contact Name:

  Duty biochemist

• Routine Telephone:

  Freeman: 0191 244 8889

  RVI: 0191 282 9719

  Freeman: 0191 244 8889

  RVI: 0191 282 9719

• Routine Email:

  nuth.dutybiochemist@nhs.net

• Specialist Test:

  Yes

  Yes

• Specialist Contact Name:

  Metabolic Clinical Scientist

  Metabolic Clinical Scientist

• Specialist Telephone:

  0191 282 9685 (Consultant Clinical Scientist)

  0191 282 0334 (Metabolic Laboratory)

  0191 282 9685 (Consultant Clinical Scientist)

  0191 282 0334 (Metabolic Laboratory)

• Specialist Email:

  tnu-tr.newcastlemetaboliclab@nhs.net

  tnu-tr.newcastlemetaboliclab@nhs.net