Myeloperoxidase Antibodies
Clinical Background:
Myeloperoxidase (MPO) antibodies are part of the first-line testing protocol for small vessel vasculitis alongside Proteinase 3 (PR3). Positive MPO antibodies point towards microscopic polyangiitis...
Myeloperoxidase (MPO) antibodies are part of the first-line testing protocol for small vessel vasculitis alongside Proteinase 3 (PR3). Positive MPO antibodies point towards microscopic polyangiitis (MPA).
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum-SST
Serum-SST
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Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
1 ml
1 ml
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Special Requirement:
None
None
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Freq Analysis:
Daily
Daily
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Add On Test:
All urgent add ons via telephone on : 0191 2821890, and must be confirmed via email to nuth.autoimmunity@nhs.net
All urgent add ons via telephone on : 0191 2821890, and must be confirmed via email to nuth.autoimmunity@nhs.net
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Quality Assurance:
UK NEQAS for Autoimmune Serology ANCA and GBM
UK NEQAS for Autoimmune Serology ANCA and GBM
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Interpretation:
Antibodies to MPO are not specific and may be detected in a range of vasculitic conditions.
Antibodies to MPO are not specific and may be detected in a range of vasculitic conditions.
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Reference Ranges:
Normal Range: 0 - 0.9 Antibody Index (AI)
Normal Range: 0 - 0.9 Antibody Index (AI)
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Other Info:
Reported as a number between 0.2 and 8.0 AI
Reported as a number between 0.2 and 8.0 AI
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 2821890
0191 2821890
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Routine Email: