Molecular Genotype
Clinical Background:
Blood group genotype testing for multitransfused, DAT positive patients or patients receiving targetted therapy with monoclonal antibodies when serological phenotyping cannot be performed. The geno...
Blood group genotype testing for multitransfused, DAT positive patients or patients receiving targetted therapy with monoclonal antibodies when serological phenotyping cannot be performed. The genotype can be used to predict blood group phenotype.
Molecular genotyping allows the determination of RhD, C, c, E, e, Cw, M/N, S/s, Kk, Jka/b, Fya/b, Doa/b, U-, Uvar and more.
Test Details
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Discipline:
Transfusion
Transfusion
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Specimen Container Adult:
6mL K2 EDTA (pink top)
6mL K2 EDTA (pink top)
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Specimen Container Paediatric:
1mL EDTA or 6mL EDTA
1mL EDTA or 6mL EDTA
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Minimum Volume Adult:
6mL
6mL
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Minimum Volume Paediatric:
1mL
1mL
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Special Requirement:
Molecular genotyping cannot be ordered through PowerChart. Samples are referred to the regional reference centre by the Transfusion laboratory as part of ongoing investigations.
Molecular genotyping cannot be ordered through PowerChart. Samples are referred to the regional reference centre by the Transfusion laboratory as part of ongoing investigations.
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Sample Stability:
Short term storage: 24 hours at room temperature.
Short term storage: 24 hours at room temperature.
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Transport Requirements:
Sample should be transported to Laboratory Medicine Reception via GP courier, hospital air-tube system or hand delivered to maintain storage conditions. Samples must not be subjected to extreme hot...
Read MoreSample should be transported to Laboratory Medicine Reception via GP courier, hospital air-tube system or hand delivered to maintain storage conditions. Samples must not be subjected to extreme hot or cold conditions prior to testing.
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Add On Test:
N/A
N/A
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Interpretation:
The molecular genotype report will state the blood group antigens identified through genetic analysis.
The molecular genotype report will state the blood group antigens identified through genetic analysis.
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Factors Affecting Result:
Samples which are old (>24 hours). Incorrect specimen type received. Clotted, haemolysed, icteric or lipaemic samples. Insufficient plasma provided.
Samples which are old (>24 hours). Incorrect specimen type received. Clotted, haemolysed, icteric or lipaemic samples. Insufficient plasma provided.
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Other Info:
This test is referred to NHSBT by the Transfusion laboratory.
This test is referred to NHSBT by the Transfusion laboratory.
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Routine Contact Name:
FH Section Leads
RVI Section Leads -
Routine Telephone:
Freeman: 0191 213 7849
RVI: 0191 282 4335Freeman: 0191 213 7849
RVI: 0191 282 4335 -
Specialist Test:
Yes
Yes
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Specialist Contact Name:
Transfusion manager
Transfusion manager
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Specialist Telephone:
0192 213 9169
0192 213 9169