Newcastle Laboratories

Liver Autoantibodies

Clinical Background:

Requests for Liver Autoantibodies will automatically be tested as follows:

Antinuclear antibody (ANA) - Reported as a titre or as Negative

Gastric Parietal Cell antibody (GPC) - reported as strongl...

Requests for Liver Autoantibodies will automatically be tested as follows:

Antinuclear antibody (ANA) - Reported as a titre or as Negative

Gastric Parietal Cell antibody (GPC) - reported as strongly positive, positive, weakly positive, negative or 'Not reportable in the presence of AMA'.

Smooth muscle antibody - reported as a titre or as negative

Anti-mitochondrial antibody (AMA) - reported as a titre or as negative.

Liver-Kidney Microsomal antibody (LKM) - reported as a titre, not reported if negative unless specifically requested.

Ribosomal antibody – reported as a titre, not reported if negative unless specifically requested.

Centromere antibody - reported if seen. Other patterns of staining may be reported if seen.

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Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Serum-SST

    Serum-SST

  • Specimen Container Paediatric:

    Serum-Plain tube

    Serum-Plain tube

  • Minimum Volume Adult:

    1 ml

    1 ml

  • Minimum Volume Paediatric:

    0.5 ml

    0.5 ml

  • Special Requirement:

    None

    None

  • Freq Analysis:

    Daily

    Daily

  • Add On Test:

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    or

    tnu-tr.bloodsciencesadditions...

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    or

    tnu-tr.bloodsciencesadditions@nhs.net (external)

    Read More
  • Quality Assurance:

    UK NEQAS for General Autoimmune Serology

    UK NEQAS for General Autoimmune Serology

  • Interpretation:

    Further investigations may be added by clinical staff depending on the result of the autoantibody screen and the clinical details provided.

    Further investigations may be added by clinical staff depending on the result of the autoantibody screen and the clinical details provided.

  • Reference Ranges:

    Please see the Reference Range section for each of the individual antibodies listed.
    Requests for Autoantibody Screen will not be repeated on a patient if a further sample is received within 6 week...

    Please see the Reference Range section for each of the individual antibodies listed.
    Requests for Autoantibody Screen will not be repeated on a patient if a further sample is received within 6 weeks of any previous sample.

    Read More
  • Other Info:

    Requests for autoantibody screen will automatically be tested as follows:

    Antinuclear antibody (ANA) - reported as a titre or as negative.

    Gastric Parietal Cell antibody (GPC) - reported as strongl...

    Requests for autoantibody screen will automatically be tested as follows:

    Antinuclear antibody (ANA) - reported as a titre or as negative.

    Gastric Parietal Cell antibody (GPC) - reported as strongly positive, positive, weakly positive, negative or 'Not reportable in the presence of AMA'.

    Smooth muscle antibody (SMA) - reported as a titre or as negative. Anti-mitochondrial antibody (AMA) - reported as a titre or as negative.

    Liver-Kidney Microsomal antibody (LKM) - reported as a titre, not reported if negative unless specifically requested.

    Ribosomal antibody – reported as a titre, not reported if negative unless specifically requested.

    Centromere antibody - reported if seen. Other patterns of staining may be reported if seen.

    Read More
  • Routine Contact Name:

    Autoimmunity Lab

  • Routine Telephone:

    0191 282 1890

    0191 282 1890

  • Routine Email:

Availability:

Liver Autoantibodies are done on a daily basis Monday to Friday, usually in the morning.

Turn Around:

2.5 routine working days

Send To:

Department of Blood Sciences

Level 3
Leazes Wing
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP

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