Liver Autoantibodies
Clinical Background:
Requests for Liver Autoantibodies will automatically be tested as follows:
Antinuclear antibody (ANA) - Reported as a titre or as Negative
Gastric Parietal Cell antibody (GPC) - reported as strongl...
Requests for Liver Autoantibodies will automatically be tested as follows:
Antinuclear antibody (ANA) - Reported as a titre or as Negative
Gastric Parietal Cell antibody (GPC) - reported as strongly positive, positive, weakly positive, negative or 'Not reportable in the presence of AMA'.
Smooth muscle antibody - reported as a titre or as negative
Anti-mitochondrial antibody (AMA) - reported as a titre or as negative.
Liver-Kidney Microsomal antibody (LKM) - reported as a titre, not reported if negative unless specifically requested.
Ribosomal antibody – reported as a titre, not reported if negative unless specifically requested.
Centromere antibody - reported if seen. Other patterns of staining may be reported if seen.
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum-SST
Serum-SST
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Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
0.5 ml
0.5 ml
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Special Requirement:
None
None
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Freq Analysis:
Daily
Daily
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Add On Test:
All urgent add ons via telephone on 0191 281890, and must be confirmed via email to nuth.autoimmunity@nhs.net
All urgent add ons via telephone on 0191 281890, and must be confirmed via email to nuth.autoimmunity@nhs.net
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Quality Assurance:
UK NEQAS for General Autoimmune Serology
UK NEQAS for General Autoimmune Serology
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Interpretation:
Further investigations may be added by clinical staff depending on the result of the autoantibody screen and the clinical details provided.
Further investigations may be added by clinical staff depending on the result of the autoantibody screen and the clinical details provided.
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Reference Ranges:
Please see the Reference Range section for each of the individual antibodies listed.
Requests for Autoantibody Screen will not be repeated on a patient if a further sample is received within 6 week...Read MorePlease see the Reference Range section for each of the individual antibodies listed.
Requests for Autoantibody Screen will not be repeated on a patient if a further sample is received within 6 weeks of any previous sample. -
Other Info:
Requests for autoantibody screen will automatically be tested as follows:
Antinuclear antibody (ANA) - reported as a titre or as negative.
Gastric Parietal Cell antibody (GPC) - reported as strongl...
Read MoreRequests for autoantibody screen will automatically be tested as follows:
Antinuclear antibody (ANA) - reported as a titre or as negative.
Gastric Parietal Cell antibody (GPC) - reported as strongly positive, positive, weakly positive, negative or 'Not reportable in the presence of AMA'.
Smooth muscle antibody (SMA) - reported as a titre or as negative. Anti-mitochondrial antibody (AMA) - reported as a titre or as negative.
Liver-Kidney Microsomal antibody (LKM) - reported as a titre, not reported if negative unless specifically requested.
Ribosomal antibody – reported as a titre, not reported if negative unless specifically requested.
Centromere antibody - reported if seen. Other patterns of staining may be reported if seen.
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email: