LDH (Lactate dehydrogenase), fluid
Clinical Background:
The serous body cavities contain a small amount of fluid that is an ultrafiltrate of plasma. When production and resorption of this ultrafiltrate are not balanced, fluid may accumulate, resulting i...
The serous body cavities contain a small amount of fluid that is an ultrafiltrate of plasma. When production and resorption of this ultrafiltrate are not balanced, fluid may accumulate, resulting in an effusion. Effusions may be classified as transudates or exudates. Transudates are usually bilateral and arise from either increased capillary hydrostatic pressure or decreased oncotic pressure secondary to congestive heart failure, fluid overload, cirrhosis or hypoalbuminemia. Exudates are usually unilateral and result from increased capillary permeability or decreased lymphatic resorption associated with infection, connective tissue disease, pancreatitis or cancer.Fluid LDH can, using Light's criteria, be used to differentiate between transudates and exudates.
Test Details
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Discipline:
Biochemistry
Biochemistry
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Specimen Container Adult:
Plain universal container
Plain universal container
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Specimen Container Paediatric:
Plain universal container
Plain universal container
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Minimum Volume Adult:
1 mL fluid
1 mL fluid
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Minimum Volume Paediatric:
1 mL fluid
1 mL fluid
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Special Requirement:
Samples which are too viscous and/or contain particulate matter after centrifugation are unsuitable for analysis.
Samples which are too viscous and/or contain particulate matter after centrifugation are unsuitable for analysis.
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Reference Ranges:
Fluid is exudate if one of the following Light’s criteria is present:
Fluid protein/serum protein ratio greater than 0.5
Fluid lactate dehydrogenase (LDH)/serum LDH ratio greater than 0.6
Fluid LDH le...Read MoreFluid is exudate if one of the following Light’s criteria is present:
Fluid protein/serum protein ratio greater than 0.5
Fluid lactate dehydrogenase (LDH)/serum LDH ratio greater than 0.6
Fluid LDH level greater than two-thirds the upper limit of the laboratory's reference range of serum LDH -
Routine Contact Name:
Duty Biochemist
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Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719Freeman: 0191 244 8889
RVI: 0191 282 9719 -
Routine Email: