Newcastle Laboratories

Lamotrigine

Clinical Background:

May be useful when assessing issues such as non-compliance. Other factors such as age, pregnancy, disease states and concomitant medication will need to be considered when interpreting plasma conce...

May be useful when assessing issues such as non-compliance. Other factors such as age, pregnancy, disease states and concomitant medication will need to be considered when interpreting plasma concentrations. As a relationship between therapeutic response or side effects and plasma concentrations has not been clearly identified, routine therapeutic plasma concentration monitoring is not required. The current recommendation is to titrate the dose upwards until optimal seizure control has been established or adverse effects become apparent. Hence dosage and plasma concentrations depend on the individual patient.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    EDTA plasma

    Gel tube unsuitable

    EDTA plasma

    Gel tube unsuitable

  • Specimen Container Paediatric:

    EDTA plasma

    Gel tube unsuitable

     

    EDTA plasma

    Gel tube unsuitable

     

  • Minimum Volume Adult:

    1 mL 

    1 mL 

  • Minimum Volume Paediatric:

    0.5 mL 

    0.5 mL 

  • Special Requirement:

    Trimethoprim interferes with this assay.

    Trimethoprim interferes with this assay.

  • Sample Stability:

    Store at 4°C

    Store at 4°C

  • Reference Ranges:

    3 - 15 mg/L

    3 - 15 mg/L

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

Sample sent to an external laboratory for testing

Turn Around:

2 weeks

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