Lactate, plasma
Clinical Background:
Lactic acid is an intermediary in carbohydrate metabolism predominantly produced in white skeletal muscle, brain, skin, renal medulla and erythrocytes and is the end product of anaerobic metabolism...
Lactic acid is an intermediary in carbohydrate metabolism predominantly produced in white skeletal muscle, brain, skin, renal medulla and erythrocytes and is the end product of anaerobic metabolism.
Lactic acidosis occurs when there is excessive lactate formation or decreased removal and occurs in two clinical settings:
Type A lactic acidosis as a consequence of hypoxia due to shock, hypovolaemia and left ventricular failure.
Type B lactic acidosis (metabolic) associated with disease (e.g. diabetes mellitus, neoplasia, liver disease), drugs/toxins (e.g., ethanol, methanol, salicylates) or inborn errors of metabolism.
Test Details
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Discipline:
Biochemistry
Biochemistry
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Specimen Container Adult:
Fluoride oxalate plasma
Fluoride oxalate plasma
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Specimen Container Paediatric:
Fluoride oxalate plasma
Fluoride oxalate plasma
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Minimum Volume Adult:
1 mL blood
1 mL blood
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Minimum Volume Paediatric:
1 mL blood
1 mL blood
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Special Requirement:
Send the sample to the laboratory as soon as possible.
Send the sample to the laboratory as soon as possible.
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Sample Stability:
Unseparated sample: day of collection
Separated sample: 8 hours at 15-25°C, 3 days at 2-8°C, >1 month at -20°CUnseparated sample: day of collection
Separated sample: 8 hours at 15-25°C, 3 days at 2-8°C, >1 month at -20°C -
Reference Ranges:
Up to 16 years: 0.6 - 2.5mmol/L
16 years and older: 0.5 - 2.2mmol/L
Up to 16 years: 0.6 - 2.5mmol/L
16 years and older: 0.5 - 2.2mmol/L
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Routine Contact Name:
Duty biochemist
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Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719
Freeman: 0191 244 8889
RVI: 0191 282 9719
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Routine Email: