Karyotype for haematological malignancy
Clinical Background:
G-banded metaphase chromosome analysis (karyotyping) can identify genome-wide structural chromosome abnormalities including balanced translocations, inversion and can identify genomic complexity in...
G-banded metaphase chromosome analysis (karyotyping) can identify genome-wide structural chromosome abnormalities including balanced translocations, inversion and can identify genomic complexity in living cells actively undergoing mitotic division. Karyotyping is vital in many haematological malignancies especially in myeloid malignancies where karyotype analysis is vital for prognosis and treatment decisions. Karyotyping will usually be performed on a bone marrow aspirate sample on request of a consultant or specialist registrar in haematology.
Test Details
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Discipline:
NEHODS
NEHODS
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Specimen Container Adult:
Lithium heparin
Lithium heparin
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Specimen Container Paediatric:
Lithium heparin
Lithium heparin
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Minimum Volume Adult:
3ml
3ml
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Minimum Volume Paediatric:
3ml
3ml
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Special Requirement:
Please complete NEHODS request form
Please complete NEHODS request form
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Sample Stability:
needs to be received within 24hrs of sampling
needs to be received within 24hrs of sampling
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Transport Requirements:
Samples should be sent to laboratory immediately.
Samples should be sent to laboratory immediately.
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Freq Analysis:
Daily
Daily
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Add On Test:
Can be added to any genetics sample where cultured cells have been stored
Can be added to any genetics sample where cultured cells have been stored
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Quality Assurance:
UK NEQAS
UK NEQAS
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Interpretation:
By genetics clinical scientist
By genetics clinical scientist
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Reference Ranges:
N/A
N/A
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Factors Affecting Result:
Quality and size of sample
Quality and size of sample
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Referenced Documents:
N/A
N/A
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Other Info:
Samples for AML will be processed within 72 hours.
Samples for AML will be processed within 72 hours.