Jo-1 Antibodies
Clinical Background:
Jo-1 antibodies are found in 25% of adult patients with autoimmune myositis and in 68% patients with anti-synthetase syndrome (myositis, arthritis, raynauds, and interstitial lung disease).
Jo-1 antibodies are found in 25% of adult patients with autoimmune myositis and in 68% patients with anti-synthetase syndrome (myositis, arthritis, raynauds, and interstitial lung disease).
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum-SST
Serum-SST
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Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
0.5 ml
0.5 ml
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Special Requirement:
None
None
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Freq Analysis:
Daily
Daily
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Add On Test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to
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Quality Assurance:
UK NEQAS for Antibodies to Nuclear and Related Antigens
UK NEQAS for Antibodies to Nuclear and Related Antigens
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Interpretation:
ANA may be negative; Jo-1 antibodies do not demonstrate the speckled ANA staining pattern seen with the other ENAs.
ANA may be negative; Jo-1 antibodies do not demonstrate the speckled ANA staining pattern seen with the other ENAs.
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Reference Ranges:
Normal Range: Negative
Normal Range: Negative
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Other Info:
Jo-1 antibodies are detected as part of the ANA and related antibodies screen and are reported as Negative or Positive.
Jo-1 antibodies are detected as part of the ANA and related antibodies screen and are reported as Negative or Positive.
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email: