HLA-B*5701 Status
Clinical Background:
Abacavir is an antiviral agent used in conjunction with others in the treatment of HIV. Abacavir is generally well tolerated but can cause hypersensitivity in 5% to 8% of patients during the first ...
Abacavir is an antiviral agent used in conjunction with others in the treatment of HIV. Abacavir is generally well tolerated but can cause hypersensitivity in 5% to 8% of patients during the first 6 weeks of treatment. Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele
Test Details
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Discipline:
Microbiology
Microbiology
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Specimen Container Adult:
Blood - EDTA
Blood - EDTA
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Specimen Container Paediatric:
Blood - EDTA
Blood - EDTA
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Minimum Volume Adult:
5 ml
5 ml
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Minimum Volume Paediatric:
1 ml
1 ml
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Special Requirement:
Send to laboratory as quickly as possible. If delays likely, refrigerate at 2-8 deg C
Send to laboratory as quickly as possible. If delays likely, refrigerate at 2-8 deg C
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Sample Stability:
Stable for up to 24 hours
Stable for up to 24 hours
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Transport Requirements:
Standard
Standard
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Add On Test:
N/A
N/A
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Quality Assurance:
Sample referred to Reference Laboratory
Sample referred to Reference Laboratory
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Reference Ranges:
None available
None available
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Factors Affecting Result:
If delays likely, refrigerate at 2-8 deg C
If delays likely, refrigerate at 2-8 deg C