Haptoglobin
Clinical Background:
Haptoglobin is a transport and acute phase protein which is synthesized in hepatocytes.
Haptoglobin binds haemoglobin in a strong haptoglobin-haemoglobin complex (Hp-Hb), the haemoglobin resulting ...
Haptoglobin is a transport and acute phase protein which is synthesized in hepatocytes.
Haptoglobin binds haemoglobin in a strong haptoglobin-haemoglobin complex (Hp-Hb), the haemoglobin resulting from pathologically elevated haemolysis.
A reduction in the level of free haptoglobin is indicative of intravascular haemolysis.
Indications for haptoglobin assays have been published and include the assessment of the severity and stage of intravascular haemolysis, evaluation of acute inflammatory processes and phenotype differentiation in paternity diagnostics.
Test Details
-
Discipline:
Biochemistry
Biochemistry
-
Specimen Container Adult:
Serum (SST or plain tube)
Serum (SST or plain tube)
-
Specimen Container Paediatric:
Serum (SST or plain tube)
Serum (SST or plain tube)
-
Minimum Volume Adult:
1.0 mL
1.0 mL
-
Minimum Volume Paediatric:
0.5 mL
0.5 mL
-
Sample Stability:
Unseparated sample: 8 days at 15-25°C
Separated sample: 3 months at 15-25°C, 8 months at 4-8°C, 3 months at -20°CUnseparated sample: 8 days at 15-25°C
Separated sample: 3 months at 15-25°C, 8 months at 4-8°C, 3 months at -20°C -
Reference Ranges:
0.30 - 2.00 g/L
0.30 - 2.00 g/L
-
Other Info:
Lithium heparin plasma sample also acceptable
Lithium heparin plasma sample also acceptable
-
Routine Contact Name:
Duty Biochemist
-
Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719
Freeman: 0191 244 8889
RVI: 0191 282 9719
-
Routine Email: