Newcastle Laboratories

Gastric Parietal Cell Antibody

Clinical Background:

Gastric parietal cell antibodies are found in patients with pernicious anaemia, they are associated with atrophic gastritis.

Gastric parietal cell antibodies are found in patients with pernicious anaemia, they are associated with atrophic gastritis.

Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Serum-SST

    Serum-SST

  • Specimen Container Paediatric:

    Serum-Plain tube

    Serum-Plain tube

  • Minimum Volume Adult:

    1 ml

    1 ml

  • Minimum Volume Paediatric:

    0.5 ml

    0.5 ml

  • Special Requirement:

    None

    None

  • Freq Analysis:

    Daily

    Daily

  • Add On Test:

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    or

    tnu-tr.bloodsciencesadditions...

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    or

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS for General Autoimmune Serology

    UK NEQAS for General Autoimmune Serology

  • Interpretation:

    These antibodies may be found in individuals with normal full blood count and normal B12, however about 3% per year will go on to develop pernicious anaemia.

    These antibodies may be found in individuals with normal full blood count and normal B12, however about 3% per year will go on to develop pernicious anaemia.

  • Reference Ranges:

    Normal Range: Negative

    Normal Range: Negative

  • Other Info:

    Gastric parietal cell antibodies are reported as part of the Liver Autoantibodies screen as Negative, Weakly Positive, Positive or Strongly Positive. If an Anti-Mitochondrial Antibody (AMA) is dete...

    Gastric parietal cell antibodies are reported as part of the Liver Autoantibodies screen as Negative, Weakly Positive, Positive or Strongly Positive. If an Anti-Mitochondrial Antibody (AMA) is detected, the GPC will be reported as 'Not reportable in the presence of an AMA' due to interfering staining from the AMA in the gastric parietal cells.

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  • Routine Contact Name:

    Autoimmunity Lab

  • Routine Telephone:

    0191 282 1890

    0191 282 1890

  • Routine Email:

Availability:

The Liver Autoantibodies assay is done on daily basis, Monday to Friday, usually in the morning.

Turn Around:

2.5 routine working days

Send To:

Department of Blood Sciences

Level 3
Leazes Wing
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP

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