Gastric Parietal Cell Antibody
Clinical Background:
Gastric parietal cell antibodies are found in patients with pernicious anaemia, they are associated with atrophic gastritis.
Gastric parietal cell antibodies are found in patients with pernicious anaemia, they are associated with atrophic gastritis.
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum-SST
Serum-SST
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Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
0.5 ml
0.5 ml
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Special Requirement:
None
None
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Freq Analysis:
Daily
Daily
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Add On Test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address
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Quality Assurance:
UK NEQAS for General Autoimmune Serology
UK NEQAS for General Autoimmune Serology
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Interpretation:
These antibodies may be found in individuals with normal full blood count and normal B12, however about 3% per year will go on to develop pernicious anaemia.
These antibodies may be found in individuals with normal full blood count and normal B12, however about 3% per year will go on to develop pernicious anaemia.
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Reference Ranges:
Normal Range: Negative
Normal Range: Negative
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Other Info:
Gastric parietal cell antibodies are reported as part of the Liver Autoantibodies screen as Negative, Weakly Positive, Positive or Strongly Positive. If an Anti-Mitochondrial Antibody (AMA) is dete...
Read MoreGastric parietal cell antibodies are reported as part of the Liver Autoantibodies screen as Negative, Weakly Positive, Positive or Strongly Positive. If an Anti-Mitochondrial Antibody (AMA) is detected, the GPC will be reported as 'Not reportable in the presence of an AMA' due to interfering staining from the AMA in the gastric parietal cells.
'Not reporatble due to heterophilic staining' due to the interfering heterophilic staing in the GPC.
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email: