Fibrinogen - Clauss
Clinical Background:
A funtional fibrinogen assay. Thrombin is added to anticoagulated plasma and the time taken for clot formation is measured. The time taken is concentration dependant (the lower the level the longer...
A funtional fibrinogen assay. Thrombin is added to anticoagulated plasma and the time taken for clot formation is measured. The time taken is concentration dependant (the lower the level the longer the time) and this assay is used in cases of fibrinolysis. It is used in conjunction with the PT-derived fibrinogen to investigate suspected dysfibrinogenaemia (the PT-Derived result will be normal, the Clauss result will be low)
Test Details
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Discipline:
Haemostasis
Haemostasis
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Specimen Container Adult:
Light blue - sodium citrate
Light blue - sodium citrate
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Specimen Container Paediatric:
Light blue - sodium citrate
Light blue - sodium citrate
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Minimum Volume Adult:
2.7mL
2.7mL
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Minimum Volume Paediatric:
1.3mL
1.3mL
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Special Requirement:
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
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Sample Stability:
24 hrs
24 hrs
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Transport Requirements:
Samples should be transported to lab without delay
Samples should be transported to lab without delay
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Freq Analysis:
Continuous
Continuous
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Add On Test:
tnu-tr.bloodsciencesadditions@nhs.net (external)
tnu-tr.bloodsciencesadditions@nhs.net (external)
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Quality Assurance:
UK NEQAS Blood Coagulation
UK NEQAS Blood Coagulation
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Reference Ranges:
Fibrinogen (Clauss) 2.1 - 4.8g/L
Note: For Haemostatic tests, paediatric reference ranges may be different to adult ranges. Please see
...Read MoreFibrinogen (Clauss) 2.1 - 4.8g/L
Note: For Haemostatic tests, paediatric reference ranges may be different to adult ranges. Please see
https://www.newcastlelaboratories.com/lab_service/core-247/
for details.
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Other Info:
Requested as a follow on test when derived fibrinogen less than 2.0g/L as part of a coagulation screen.
Requested as a follow on test when derived fibrinogen less than 2.0g/L as part of a coagulation screen.
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Routine Contact Name:
RVI or Freeman Section Leaders
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Routine Telephone:
RVI: 0191 2820332, Freeman: 0191 2231195
RVI: 0191 2820332, Freeman: 0191 2231195
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Specialist Test:
No
No
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Specialist Contact Name:
Haematology and Haemostasis Healthcare Scientist
Haematology and Haemostasis Healthcare Scientist
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Specialist Telephone:
0191 2139758
0191 2139758
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Specialist Email:
alison.brown93@nhs.net
alison.brown93@nhs.net