Newcastle Laboratories

Ferritin

Clinical Background:

Ferritin levels reflect the amount of stored iron in the body; ferritin is the main storage protein for iron inside of cells. It is the most useful indicator of iron deficiency, as the ferritin sto...

Ferritin levels reflect the amount of stored iron in the body; ferritin is the main storage protein for iron inside of cells. It is the most useful indicator of iron deficiency, as the ferritin stores can be significantly decreased before any fall in the serum iron concentration occurs.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Serum-SST

    Serum-SST

  • Specimen Container Paediatric:

    Serum-Plain tube

    Serum-Plain tube

  • Minimum Volume Adult:

    1 mL blood

    1 mL blood

  • Minimum Volume Paediatric:

    0.5 mL blood

    0.5 mL blood

  • Sample Stability:

    Unseparated: Unknown
    Separated:
    at +15° to +25°C: 24 hours
    at +2° to +8°C: 7 days

    at -20C: 1 year

    Unseparated: Unknown
    Separated:
    at +15° to +25°C: 24 hours
    at +2° to +8°C: 7 days

    at -20C: 1 year

  • Interpretation:

    GP Adult haematology guidelines - click here

    Ferritin is found in serum in low concentrations and is directly proportional to the body’s Iron stores. Serum ferritin concentration, when analysed wit...

    GP Adult haematology guidelines - click here

    Ferritin is found in serum in low concentrations and is directly proportional to the body’s Iron stores. Serum ferritin concentration, when analysed with other factors such as serum iron, TIBC and tissue iron stores, is valuable in the diagnosis of iron-deficiency anaemias, anaemias of chronic infection and conditions such as thalassaemia and haemochromatosis that are associated with iron overload. Measurement of serum ferritin is particularly valuable in distinguishing iron-deficiency anaemias caused by low iron stores from those resulting from inadequate iron utilisation.
    Apart from iron storage serum ferritin is also an acute phase reactant protein.

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  • Reference Ranges:

    Paediatric: Consult paediatric haematologist for interpretation.
    Adult
    < 12 µg/L complete absence of stored iron
    < 20 µg/L indicates iron depletion
    > 60 µg/L iron deficiency unlikely (chronic disea...

    Paediatric: Consult paediatric haematologist for interpretation.
    Adult
    < 12 µg/L complete absence of stored iron
    < 20 µg/L indicates iron depletion
    > 60 µg/L iron deficiency unlikely (chronic disease)
    > 300 µg/L may indicate iron overload in men and post-menopausal women
    > 200 µg/L may indicate iron overload in pre-menopausal women

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  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

All times
All sites

Turn Around:

4 hours

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