Newcastle Laboratories

Factor VII Assay

Clinical Background:

Factor VII (also known as Pro-convertin) is a vitamin K sensitive coagulation protein, that is synthesised in the liver. It's role in the Haemostatic process is to initiate coagulation in conjuncti...

Factor VII (also known as Pro-convertin) is a vitamin K sensitive coagulation protein, that is synthesised in the liver. It's role in the Haemostatic process is to initiate coagulation in conjunction with tissue factor (TF). It has the shortest half like of the coagulation serine proteases. Deficiency of Factor VII results in a Haemophilia like bleeding syndrome. The PT is prolonged but the APTT is normal in cases of Factor VII deficiency

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Test Details

  • Discipline:

    Haemostasis

    Haemostasis

  • Specimen Container Adult:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Specimen Container Paediatric:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Minimum Volume Adult:

    2.7mL

    2.7mL

  • Minimum Volume Paediatric:

    1.3mL

    1.3mL

  • Special Requirement:

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

  • Sample Stability:

    4 hrs

    4 hrs

  • Transport Requirements:

    Samples should be transported to lab without delay

    Samples should be transported to lab without delay

  • Freq Analysis:

    As required or weekly

    As required or weekly

  • Add On Test:

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    tnu-tr.bloodsciencesadditions@nh...

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS Blood Coagulation

    UK NEQAS Blood Coagulation

  • Reference Ranges:

    50 - 150%

    50 - 150%

  • Other Info:

    A quantitative assay of coagulation factor VII.

    A quantitative assay of coagulation factor VII.

  • Routine Contact Name:

    Peter Strong

  • Routine Telephone:

    0191 282 0332

    0191 282 0332

  • Routine Email:

  • Specialist Test:

    Yes

    Yes

  • Specialist Contact Name:

    Haematology/Haemostasis Health care Scientist

    Haematology/Haemostasis Health care Scientist

  • Specialist Telephone:

    0191 213 9758

    0191 213 9758

Availability:

Discuss with laboratory.

Out of hours discuss with on call Specialist Registrar.

Turn Around:

14 days, urgent on request

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