Factor IX Assay
Clinical Background:
Factor IX (also known as Christmas Factor, after the original case) is a vitamin K sensitive coagulation protein, synthesised primarily in the liver. The gene for factor IX is on the X chromosome a...
Factor IX (also known as Christmas Factor, after the original case) is a vitamin K sensitive coagulation protein, synthesised primarily in the liver. The gene for factor IX is on the X chromosome and the disorder deficiency produces (Haemophilia B) is a recessive X-linked bleeding disorder. Factor IX uses Factor VIII as a co-factor in the generation of Factor Xa. The PT is normal and the APTT is prolonged in cases of Factor IX deficiency
Test Details
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Discipline:
Haemostasis
Haemostasis
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Specimen Container Adult:
Light blue - sodium citrate
Light blue - sodium citrate
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Specimen Container Paediatric:
Light blue - sodium citrate
Light blue - sodium citrate
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Minimum Volume Adult:
2.7mL
2.7mL
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Minimum Volume Paediatric:
1.3mL
1.3mL
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Special Requirement:
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
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Sample Stability:
4 hrs
4 hrs
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Transport Requirements:
Samples should be transported to lab without delay
Samples should be transported to lab without delay
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Freq Analysis:
As required or weekly
As required or weekly
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Add On Test:
tnu-tr.bloodsciencesadditions@nhs.net (external)
tnu-tr.bloodsciencesadditions@nhs.net (external)
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Quality Assurance:
UK NEQAS Blood Coagulation
UK NEQAS Blood Coagulation
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Reference Ranges:
50 - 150IU/dL
Note: For Haemostatic tests, paediatric reference ranges may be different to adult ranges. Please see
https://www.newcastlelaboratories.com/lab_service/core-247/
for details.
50 - 150IU/dL
Note: For Haemostatic tests, paediatric reference ranges may be different to adult ranges. Please see
https://www.newcastlelaboratories.com/lab_service/core-247/
for details.
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Other Info:
A quantitative assay of coagulation factor IX.
A quantitative assay of coagulation factor IX.
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Routine Contact Name:
RVI or Freeman Section Leaders
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Routine Telephone:
RVI: 0191 2820332, Freeman: 0191 2231195
RVI: 0191 2820332, Freeman: 0191 2231195
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Specialist Test:
Yes
Yes
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Specialist Contact Name:
Haematology and Haemostasis Healthcare Scientist
Haematology and Haemostasis Healthcare Scientist
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Specialist Telephone:
0191 2139758
0191 2139758
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Specialist Email:
alison.brown93@nhs.net
alison.brown93@nhs.net