Etanercept
Clinical Background:
The measurement of anti-TNF alpha biologicals is a useful tool in managing patients who fail to respond (primary failure) or who go on to lose response (secondary failure) to treatment. Monitoring ...
The measurement of anti-TNF alpha biologicals is a useful tool in managing patients who fail to respond (primary failure) or who go on to lose response (secondary failure) to treatment. Monitoring drug levels allows for a personalised approach to drug optimisation by appropriate dose escalation/de-escalation or drug switching/withdrawal.
Test Details
-
Discipline:
Biochemistry
Biochemistry
-
Specimen Container Adult:
Serum (SST or plain tube)
Serum (SST or plain tube)
-
Specimen Container Paediatric:
Serum (SST or plain tube)
Serum (SST or plain tube)
-
Minimum Volume Adult:
1 mL
1 mL
-
Minimum Volume Paediatric:
1 mL
1 mL
-
Special Requirement:
Ideally take sample just before drug administration (trough level)
Ideally take sample just before drug administration (trough level)
-
Sample Stability:
Keep in fridge until transport.
If transport is going to be delayed by > 5 days, freeze at -20°C
Keep in fridge until transport.
If transport is going to be delayed by > 5 days, freeze at -20°C
-
Transport Requirements:
First class post at ambient temperature
First class post at ambient temperature
-
Other Info:
Lithium heparin, citrate and EDTA plasma samples also acceptable
Lithium heparin, citrate and EDTA plasma samples also acceptable
-
Routine Contact Name:
Duty Biochemist
-
Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719Freeman: 0191 244 8889
RVI: 0191 282 9719 -
Routine Email: