Newcastle Laboratories

D-Dimers

Clinical Background:

D-Dimer is one of the early products from the breakdown of cross-linked fibrin by the fibrinolytic system. It is used in the investigation of suspected DVT/PE and in the monitoring of DIC. The test...

D-Dimer is one of the early products from the breakdown of cross-linked fibrin by the fibrinolytic system. It is used in the investigation of suspected DVT/PE and in the monitoring of DIC. The test has a very high Negative Predictive Value (NPV) and is part of the Wells score used to determine likelyhood of thrombosis. The positive predictive value of the test is not as high and a positive result is not diagnotic of DVT/PE

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Test Details

  • Discipline:

    Haemostasis

    Haemostasis

  • Specimen Container Adult:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Specimen Container Paediatric:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Minimum Volume Adult:

    2.7mL

    2.7mL

  • Minimum Volume Paediatric:

    1.3mL

    1.3mL

  • Special Requirement:

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

  • Sample Stability:

    8 hrs

    8 hrs

  • Transport Requirements:

    Samples should be transported to lab without delay

    Samples should be transported to lab without delay

  • Freq Analysis:

    Continuous

    Continuous

  • Add On Test:

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    tnu-tr.bloodsciencesadditions@nh...

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS Blood Coagulation

    UK NEQAS Blood Coagulation

  • Reference Ranges:

    Less than 230ng/mL. If used in DVT pathway <500 ng/ml

    Less than 230ng/mL. If used in DVT pathway <500 ng/ml

  • Other Info:

    A quantitative assay of fibrin degradation product D-Dimer.

    A quantitative assay of fibrin degradation product D-Dimer.

  • Routine Contact Name:

    Peter Strong

  • Routine Telephone:

    0191 282 0332

    0191 282 0332

  • Routine Email:

  • Specialist Test:

    No

    No

  • Specialist Contact Name:

    Haematology/Haemostasis Health care Scientist

    Haematology/Haemostasis Health care Scientist

  • Specialist Telephone:

    0191 213 9758

    0191 213 9758

Availability:

All times, both sites

Turn Around:

Urgent within 1 hour.

Routine within 4 hours.

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