Newcastle Laboratories

Centromere Antibodies

Clinical Background:

They are found in 70-80% of cases of limited cutaneous scleroderma (CREST syndrome).

They are found in 70-80% of cases of limited cutaneous scleroderma (CREST syndrome).

Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Serum-SST

    Serum-SST

  • Specimen Container Paediatric:

    Serum-Plain tube

    Serum-Plain tube

  • Minimum Volume Adult:

    1 ml

    1 ml

  • Minimum Volume Paediatric:

    0.5 ml

    0.5 ml

  • Special Requirement:

    None

    None

  • Freq Analysis:

    Daily

    Daily

  • Add On Test:

    All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address

    nuth.autoimmunity@nhs.net

     

    All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address

    nuth.autoimmunity@nhs.net

     

  • Quality Assurance:

    UK NEQAS for Antibodies to Nuclear and Related Antigens

    UK NEQAS for Antibodies to Nuclear and Related Antigens

  • Interpretation:

    None

    None

  • Reference Ranges:

    Normal Range: Negative

    Normal Range: Negative

  • Other Info:

    Centromere antibodies are requested as part of the ANA and related antibodies test but are detected on HEp-2 substrate as part of the Autoantibody Screen .

    Centromere antibodies are requested as part of the ANA and related antibodies test but are detected on HEp-2 substrate as part of the Autoantibody Screen .

  • Routine Contact Name:

    Autoimmunity Lab

  • Routine Telephone:

    0191 282 1890

    0191 282 1890

  • Routine Email:

Availability:

Centromere antibodies are detected by BioPlex 2200 multiplex analyser and are run on a daily basis.

Turn Around:

3 routine working days

Send To:

Department of Blood Sciences

Level 3
Leazes Wing
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP

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