Newcastle Laboratories

Arsenic, urine

Clinical Background:

Arsenic is excreted in the urine and measurement of the urinary arsenic output is the determination of choice. Concentrations both in blood and urine will increase after the consumption of sea food...

Arsenic is excreted in the urine and measurement of the urinary arsenic output is the determination of choice. Concentrations both in blood and urine will increase after the consumption of sea food. Separation of the arsenic species in urine is necessary to distinguish between the toxic and non-toxic forms. Alternatively known sources of non-toxic arsenic should be excluded from the diet some five days before making an assessment.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Urine-Random

    Urine-Random

  • Specimen Container Paediatric:

    Urine-Random

    Urine-Random

  • Minimum Volume Adult:

    20 mL aliquot in a plain universal

    20 mL aliquot in a plain universal

  • Minimum Volume Paediatric:

    20 mL aliquot in a plain universal

    20 mL aliquot in a plain universal

  • Transport Requirements:

    By 1st class post to referral lab.

    By 1st class post to referral lab.

  • Interpretation:

    Symptoms of arsenic poisoning begin with headaches, confusion, severe diarrhea, and drowsiness. As the poisoning develops, convulsions and changes in fingernail pigmentation called leukonychia stri...

    Symptoms of arsenic poisoning begin with headaches, confusion, severe diarrhea, and drowsiness. As the poisoning develops, convulsions and changes in fingernail pigmentation called leukonychia striata, Mees' lines, or Aldrich-Mees' lines may occur. When the poisoning becomes acute, symptoms may include diarrhea, vomiting, blood in the urine, cramping muscles, hair loss, stomach pain, and more convulsions. The organs of the body that are usually affected by arsenic poisoning are the lungs, skin, kidneys, and liver. The final result of arsenic poisoning is coma and death.

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  • Reference Ranges:

    Provided on report from referral laboratory.

    Provided on report from referral laboratory.

  • Factors Affecting Result:

    For arsenic analysis, diet must be free of seafood for 5 days.

    For arsenic analysis, diet must be free of seafood for 5 days.

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

    - For external users: TNU-Tr.duty.biochemist@nhs.net

    - For Trust users: DutyBiochemist@nuth.nhs.uk

  • Specialist Test:

    Yes

    Yes

Availability:

Referred to an external laboratory for analysis.

Turn Around:

Within 2 full access days

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