Aquaporin 4 antibodies
Clinical Background:
Aquaporin 4 (AQP4) is the major autoantigen in neuromyelitis optica (NMO, or Devic's disease). Antibodies to AQP4 are found in >80% of NMO patients and around 50% of patients with longitudinally ex...
Aquaporin 4 (AQP4) is the major autoantigen in neuromyelitis optica (NMO, or Devic's disease). Antibodies to AQP4 are found in >80% of NMO patients and around 50% of patients with longitudinally extensive transverse myelitis. They are infrequent in patients with optic neuritis without spinal cord involvement.
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum or CSF
Serum or CSF
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Specimen Container Paediatric:
Serum or CSF
Serum or CSF
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
1 ml
1 ml
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Add On Test:
All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address
tnu-tr.bloodsciencesadditions@nhs.net (internal)
or
Read MoreAll urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address
tnu-tr.bloodsciencesadditions@nhs.net (internal)
or
tnu-tr.bloodsciencesadditions@nhs.net (external)
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Quality Assurance:
IfQ autoantibodies against Neuronal antigens
IfQ autoantibodies against Neuronal antigens
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Reference Ranges:
Normal range:Negative
Normal range:Negative
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email:
nuth.autoimmunity@nhs.net