Newcastle Laboratories

Anti-Xa Assay

Clinical Background:

The Anti-Xa assay is used to monitor the degree of anticoagulation effect in patients on Low Molecular Weight Heparin. It is a chromogenic assay and is used instead of the APTR for LMWH due to the ...

The Anti-Xa assay is used to monitor the degree of anticoagulation effect in patients on Low Molecular Weight Heparin. It is a chromogenic assay and is used instead of the APTR for LMWH due to the non linear, variable effect on the APTT

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Test Details

  • Discipline:

    Haemostasis

    Haemostasis

  • Specimen Container Adult:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Specimen Container Paediatric:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Minimum Volume Adult:

    2.7mL

    2.7mL

  • Minimum Volume Paediatric:

    1.3mL

    1.3mL

  • Special Requirement:

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

  • Sample Stability:

    2 hrs

    2 hrs

  • Transport Requirements:

    Samples should be transported to lab without delay

    Samples should be transported to lab without delay

  • Freq Analysis:

    On request

    On request

  • Add On Test:

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    tnu-tr.bloodsciencesadditions@nhs....

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS Blood Coagulation

    UK NEQAS Blood Coagulation

  • Reference Ranges:

    Target therapeutic range depends on indication and whether treatment is prophylactic or therapeutic

    Target therapeutic range depends on indication and whether treatment is prophylactic or therapeutic

  • Other Info:

    Quantitative assay, primarily for LMWH concentrations.

    Quantitative assay, primarily for LMWH concentrations.

  • Routine Contact Name:

    Peter Strong

  • Routine Telephone:

    0191 282 0332

    0191 282 0332

  • Routine Email:

    peter.strong@nuth.nhs.uk

  • Specialist Test:

    No

    No

  • Specialist Contact Name:

    Haematology/Haemostasis Health care Scientist

    Haematology/Haemostasis Health care Scientist

  • Specialist Telephone:

    0191 213 9758

    0191 213 9758

Availability:

All times, both sites

Turn Around:

Usually within 3 hours.

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