Anti-Xa Assay
Clinical Background:
The Anti-Xa assay is used to monitor the degree of anticoagulation effect in patients on Low Molecular Weight Heparin. It is a chromogenic assay and is used instead of the APTR for LMWH due to the ...
The Anti-Xa assay is used to monitor the degree of anticoagulation effect in patients on Low Molecular Weight Heparin. It is a chromogenic assay and is used instead of the APTR for LMWH due to the non linear, variable effect on the APTT
Test Details
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Discipline:
Haemostasis
Haemostasis
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Specimen Container Adult:
Light blue - sodium citrate
Light blue - sodium citrate
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Specimen Container Paediatric:
Light blue - sodium citrate
Light blue - sodium citrate
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Minimum Volume Adult:
2.7mL
2.7mL
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Minimum Volume Paediatric:
1.3mL
1.3mL
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Special Requirement:
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
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Sample Stability:
2 hrs
2 hrs
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Transport Requirements:
Samples should be transported to lab without delay
Samples should be transported to lab without delay
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Freq Analysis:
On request
On request
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Add On Test:
tnu-tr.bloodsciencesadditions@nhs.net (external)
tnu-tr.bloodsciencesadditions@nhs.net (external)
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Quality Assurance:
UK NEQAS Blood Coagulation
UK NEQAS Blood Coagulation
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Reference Ranges:
Target therapeutic range depends on indication and whether treatment is prophylactic or therapeutic
Target therapeutic range depends on indication and whether treatment is prophylactic or therapeutic
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Other Info:
Quantitative assay, primarily for LMWH concentrations.
Quantitative assay, primarily for LMWH concentrations.
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Routine Contact Name:
RVI or Freeman Section Leaders
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Routine Telephone:
RVI: 0191 2820332, Freeman: 0191 2231195
RVI: 0191 2820332, Freeman: 0191 2231195
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Specialist Test:
No
No
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Specialist Contact Name:
Haematology and Haemostasis Healthcare Scientist
Haematology and Haemostasis Healthcare Scientist
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Specialist Telephone:
0191 2139758
0191 2139758
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Specialist Email:
alison.brown93@nhs.net
alison.brown93@nhs.net