Anti-Nuclear Antibodies
Clinical Background:
ANAs will be reported as part of an Autoantibody Screen. They are reported, either as Negative or as a titre (dilution) at which the ANA is last seen as positive. The pattern of ANA is also reporte...
ANAs will be reported as part of an Autoantibody Screen. They are reported, either as Negative or as a titre (dilution) at which the ANA is last seen as positive. The pattern of ANA is also reported as part of the Autoantibody Screen and this can give an indication of possible significant antibodies.
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum-SST
Serum-SST
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Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
0.5 ml
0.5 ml
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Special Requirement:
None
None
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Freq Analysis:
Daily
Daily
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Add On Test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address
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Quality Assurance:
UK NEQAS for Antibodies to Nuclear and Related Antigens
UK NEQAS for Antibodies to Nuclear and Related Antigens
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Interpretation:
Antinuclear antibodies may be associated with connective tissue diseases but are non-specific and may also occur in other conditions especially infections.
Antinuclear antibodies may be associated with connective tissue diseases but are non-specific and may also occur in other conditions especially infections.
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Reference Ranges:
Adult Normal Range: <1/80
Paediatric Normal Range: <1/20
Adult Normal Range: <1/80
Paediatric Normal Range: <1/20
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Other Info:
Reported as Negative or a titration value for Positive samples. ANA is useful in the diagnosis of SLE and other connective tissue diseases but is not a useful tool for assessing disease activity an...
Read MoreReported as Negative or a titration value for Positive samples. ANA is useful in the diagnosis of SLE and other connective tissue diseases but is not a useful tool for assessing disease activity and response to treatment; serial measurement of ANA is therefore discouraged.
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email: