Newcastle Laboratories

Anti-Amphiphysin Antibody

Clinical Background:

Anti-amphiphysin antibodies bind widely in the brain to pre-synaptic terminals, giving variable cytoplasmic staining. Association is with a range of neurological disorders including: subacute senso...

Anti-amphiphysin antibodies bind widely in the brain to pre-synaptic terminals, giving variable cytoplasmic staining. Association is with a range of neurological disorders including: subacute sensory neuropathy; sensorimotor peripheral neuropathy; paraneoplastic stiff-person syndrome. Commonly associated tumours are small cell lung cancer and breast cancer.

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Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Serum-SST

    Serum-SST

  • Specimen Container Paediatric:

    Serum-Plain tube

    Serum-Plain tube

  • Minimum Volume Adult:

    1 ml

    1 ml

  • Minimum Volume Paediatric:

    0.5 ml

    0.5 ml

  • Special Requirement:

    None

    None

  • Add On Test:

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    or

    tnu-tr.bloodsciencesadditions@nhs...

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    or

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Interpretation:

    None

    None

  • Reference Ranges:

    Normal Range: Negative.

    Normal Range: Negative.

  • Other Info:

    Reported as Negative or Positive

    Reported as Negative or Positive

  • Routine Contact Name:

    Jonathan Wake
  • Routine Telephone:

    0191 282 1890

    0191 282 1890

  • Routine Email:

    jonathan.wake@nuth.nhs.uk

Availability:

Sent to an external laboratory for testing.

Turn Around:

21 routine working days

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