Newcastle Laboratories

Angiotensin converting enzyme, CSF

Clinical Background:

Used to diagnose neurosarcoidosis (complication of sarcoidosis, in which inflammation occurs in the brain, spinal cord and other areas of the nervous system). Sarcoidosis is a disease involving abn...

Used to diagnose neurosarcoidosis (complication of sarcoidosis, in which inflammation occurs in the brain, spinal cord and other areas of the nervous system). Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas.

Increased amounts of ACE often correlate to the presence of granulomas secondary to sarcoidosis. About 50-80 % of patients with active sarcoidosis will have elevated levels of ACE.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    CSF in plain tube/universal

    CSF in plain tube/universal

  • Specimen Container Paediatric:

    CSF in plain tube/universal

    CSF in plain tube/universal

  • Minimum Volume Adult:

    0.5 mL

    0.5 mL

  • Minimum Volume Paediatric:

    0.5 mL

    0.5 mL

  • Special Requirement:

    Store at 4°C Monday to Thursday;  Frozen Friday to Sunday

    Store at 4°C Monday to Thursday;  Frozen Friday to Sunday

  • Transport Requirements:

    Post at ambient temperature

    Post at ambient temperature

  • Reference Ranges:

    0.1-2.0 IU/L

    0.1-2.0 IU/L

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889

    RVI: 0191 282 9719

    Freeman: 0191 244 8889

    RVI: 0191 282 9719

  • Routine Email:

    - For external users: TNU-Tr.duty.biochemist@nhs.net

    - For Trust users: DutyBiochemist@nuth.nhs.uk

Availability:

Sample sent to an external laboratory for analysis

Turn Around:

4 weeks

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