Alanine aminotransferase, serum
Clinical Background:
ALT is an intracellular cytoplasmic enzyme. It is widely distributed throughout the body’s tissues, with the greatest amounts in liver and the kidneys. It is a key enzyme in gluconeogenesis. ALT pr...
ALT is an intracellular cytoplasmic enzyme. It is widely distributed throughout the body’s tissues, with the greatest amounts in liver and the kidneys. It is a key enzyme in gluconeogenesis. ALT present in the plasma is presumed to be derived from the normal turnover of tissue cells; increased quantities are found in tissue damage (particularly hepatic cell damage).
Test Details
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Discipline:
Biochemistry
Biochemistry
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Specimen Container Adult:
Serum (SST or plain tube)
Serum (SST or plain tube)
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Specimen Container Paediatric:
Serum (SST or plain tube)
Serum (SST or plain tube)
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Minimum Volume Adult:
1 mL blood
1 mL blood
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Minimum Volume Paediatric:
0.5 mL blood
0.5 mL blood
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Sample Stability:
Unseparated sample: 4 days
Separate sample: 3 days at 15-25C, 7 days at 2-8C, >7 days at -80CUnseparated sample: 4 days
Separate sample: 3 days at 15-25C, 7 days at 2-8C, >7 days at -80C -
Reference Ranges:
All ages: 0 - 40 U/L
All ages: 0 - 40 U/L
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Factors Affecting Result:
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Other Info:
Lithium heparin plasma sample also acceptable
Lithium heparin plasma sample also acceptable
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Routine Contact Name:
Duty Biochemist
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Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719Freeman: 0191 244 8889
RVI: 0191 282 9719 -
Routine Email: