Alpha1-antitrypsin phenotyping, serum
Clinical Background:
Used to identify homozygous and heterozygous phenotypes of A1AT deficiency.
Used to identify homozygous and heterozygous phenotypes of A1AT deficiency.
Test Details
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Discipline:
Biochemistry
Biochemistry
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Specimen Container Adult:
Serum
Serum
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Specimen Container Paediatric:
Serum
Serum
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Minimum Volume Adult:
2 mL blood
2 mL blood
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Minimum Volume Paediatric:
2 mL blood
2 mL blood
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Special Requirement:
Store sample at 4°C
Store sample at 4°C
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Transport Requirements:
Post at room temperature
Post at room temperature
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Reference Ranges:
There are over 40 A1AT phenotypes, with most associated with normal quantitative levels of protein. Most normal individuals have the M phenotype with over 99% of M phenotypes being genetically MM. ...
Read MoreThere are over 40 A1AT phenotypes, with most associated with normal quantitative levels of protein. Most normal individuals have the M phenotype with over 99% of M phenotypes being genetically MM. The most common alleles associated with a quantitative deficiency are Z and S with the majority being ZZ.
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Routine Contact Name:
Duty Biochemist
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Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719Freeman: 0191 244 8889
RVI: 0191 282 9719 -
Routine Email: