Newcastle Laboratories

Alpha1-antitrypsin phenotyping, serum

Clinical Background:

Phenotyping is performed primarily: a) To detect neonates with liver disease due to PiZZ; this is clinically similar to that caused by biliary atresia, which may require urgent surgical interventio...

Phenotyping is performed primarily: a) To detect neonates with liver disease due to PiZZ; this is clinically similar to that caused by biliary atresia, which may require urgent surgical intervention. b) To detect AAT deficiency in older patients with lung disease. c) Family studies with a view to pre-natal diagnosis (in conjunction with genotyping).

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    EDTA plasma or serum SST

    EDTA plasma or serum SST

  • Specimen Container Paediatric:

    EDTA plasma or serum SST

    EDTA plasma or serum SST

  • Minimum Volume Adult:

    2 mL blood

    2 mL blood

  • Minimum Volume Paediatric:

    2 mL blood

    2 mL blood

  • Special Requirement:

    Store sample at 4°C

    Store sample at 4°C

  • Transport Requirements:

    Post at room temperature

    Post at room temperature

  • Interpretation:

    Provided on report

    Provided on report

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

Sample sent to an external laboratory for analysis

Turn Around:

2 weeks

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