Alpha1-antitrypsin phenotyping, serum
Clinical Background:
Phenotyping is performed primarily: a) To detect neonates with liver disease due to PiZZ; this is clinically similar to that caused by biliary atresia, which may require urgent surgical interventio...
Phenotyping is performed primarily: a) To detect neonates with liver disease due to PiZZ; this is clinically similar to that caused by biliary atresia, which may require urgent surgical intervention. b) To detect AAT deficiency in older patients with lung disease. c) Family studies with a view to pre-natal diagnosis (in conjunction with genotyping).
Test Details
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Discipline:
Biochemistry
Biochemistry
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Specimen Container Adult:
EDTA plasma or serum SST
EDTA plasma or serum SST
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Specimen Container Paediatric:
EDTA plasma or serum SST
EDTA plasma or serum SST
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Minimum Volume Adult:
2 mL blood
2 mL blood
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Minimum Volume Paediatric:
2 mL blood
2 mL blood
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Special Requirement:
Store sample at 4°C
Store sample at 4°C
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Transport Requirements:
Post at room temperature
Post at room temperature
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Interpretation:
Provided on report
Provided on report
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Routine Contact Name:
Duty Biochemist
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Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719Freeman: 0191 244 8889
RVI: 0191 282 9719 -
Routine Email: