Alpha1-antitrypsin, faecal
Clinical Background:
Investigation of suspected protein losing enteropathy (PLE). In protein losing enteropathy, serum proteins are lost into the gut. One way to assess this is to measure the concentration of alpha-1 a...
Investigation of suspected protein losing enteropathy (PLE). In protein losing enteropathy, serum proteins are lost into the gut. One way to assess this is to measure the concentration of alpha-1 antitrypsin in stool samples. Alpha-1 antitrypsin is a protease inhibitor, making it resistant to degradation by proteases in the stool sample.
Test Details
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Discipline:
Biochemistry
Biochemistry
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Specimen Container Adult:
Faeces sample
Faeces sample
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Specimen Container Paediatric:
Faeces sample
Faeces sample
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Minimum Volume Adult:
10g faeces
10g faeces
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Minimum Volume Paediatric:
10g faeces
10g faeces
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Special Requirement:
Ward: send to the laboratory within 1 hour of sample collection
External laboratories: send frozen to the laboratory
Ward: send to the laboratory within 1 hour of sample collection
External laboratories: send frozen to the laboratory
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Transport Requirements:
Must be transported on dry ice
Must be transported on dry ice
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Reference Ranges:
0.00 – 0.48 mg/gww (grams wet weight of faeces)
0.00 – 0.48 mg/gww (grams wet weight of faeces)
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Routine Contact Name:
Duty Biochemist
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Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719Freeman: 0191 244 8889
RVI: 0191 282 9719 -
Routine Email: